ABSTRACT
The role of the nurse is based on providing comprehensive quality care to the healthy or sick person and accompanying him/her in the healing and rehabilitation process, and if nec-essary, at the time of death. Objective: To examine the role of nursing in the Covid-19 pandemic through a systematic review. Methodology: A systematic investigation was carried out in the scientific databases PubMed, SciElo, Google Scholar, Nursing Journal combining the Boolean operators AND and OR, in Spanish, English and Portuguese. Results: The literary search reported 1243 documents after the ap-plication of the selection criteria and evaluative reading, 32 articles were included for analysis due to their belonging and contribution to the fulfillment of the objective. Conclusions: It is possible to affirm that the pandemic caused by Covid-19 placed the health systems in different challenges, where the nurse played a transcendental and recognized role, standing out for being the heart and fundamental pillar in the different levels of care, demonstrating their safety and leadership by being in a frontline scenario. © 2021, Venezuelan Society of Pharmacology and Clinical and Therapeutic Pharmacology. All rights reserved.